: An Inquiry into the Causes and Effects of the Variolae Vaccinae A Disease Discovered in Some of the Western Counties of England Particularly Gloucestershire and Known by the Name of the Cow Pox by Jenner Edward - Smallpox Vaccination Early works to 1800; V

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BY EDWARD JENNER, M.D. F.R.S. &c.

LUCRETIUS.

In the present age of scientific investigation, it is remarkable that a disease of so peculiar a nature as the Cow Pox, which has appeared in this and some of the neighbouring counties for such a series of years, should so long have escaped particular attention. Finding the prevailing notions on the subject, both among men of our profession and others, extremely vague and indeterminate, and conceiving that facts might appear at once both curious and useful, I have instituted as strict an inquiry into the causes and effects of this singular malady as local circumstances would admit.

The following pages are the result, which, from motives of the most affectionate regard, are dedicated to you, by

Your sincere Friend, EDWARD JENNER.

Berkeley, Gloucestershire, June 21st, 1798.

The deviation of Man from the state in which he was originally placed by Nature seems to have proved to him a prolific source of Diseases. From the love of splendour, from the indulgences of luxury, and from his fondness for amusement, he has familiarised himself with a great number of animals, which may not originally have been intended for his associates.

The Wolf, disarmed of ferocity, is now pillowed in the lady's lap. The Cat, the little Tyger of our island, whose natural home is the forest, is equally domesticated and caressed. The Cow, the Hog, the Sheep, and the Horse, are all, for a variety of purposes, brought under his care and dominion.

Thus the disease makes its progress from the Horse to the nipple of the Cow, and from the Cow to the Human Subject.

Morbid matter of various kinds, when absorbed into the system, may produce effects in some degree similar; but what renders the Cow-pox virus so extremely singular, is, that the person who has been thus affected is for ever after secure from the infection of the Small Pox; neither exposure to the variolous effluvia, nor the insertion of the matter into the skin, producing this distemper.

In support of so extraordinary a fact, I shall lay before my Reader a great number of instances.

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